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Drug Discovery Toxicology: From Target Assessment to Translational Biomarkers
Hoofdkenmerken
Auteur: Yvonne Will; J. Eric McDuffie; Andrew J. Olaharski; Brandon D. Jeffy
Titel: Drug Discovery Toxicology: From Target Assessment to Translational Biomarkers
Uitgever: Wiley Global Research (STMS)
ISBN: 9781119053392
ISBN boekversie: 9781119053330
Editie: 1
Prijs: € 206,22
Verschijningsdatum: 22-03-2016
Inhoudelijke kenmerken
Categorie: Pharmacology
Taal: English
Imprint: Wiley-Blackwell
Technische kenmerken
Verschijningsvorm: E-book
 

Inhoudsopgave:

As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug safety experiments are both practical and useful • Covers a variety of key topics – safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and –omics tools • Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods • Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices
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